药物合成用无水氟化铁的制备及其10吨/年规模化生产流程设计

… We have decided to extend our work to iron analogues. To … (III), there exists no direct and simple method for the synthesis … Iron(III) hydroxide was prepared from 1.0 g of anhydrous iron(…

… fluorine at ambient temperature in anhydrous HF (aHF) offer a milder approach to the preparation of various fluorides … in the highest oxidation states [ie, Ni(IV), Ag(III), Mn(IV), Cr(V), Au(V)…

… to grow metastable phases, anhydrous or hydrated [3]. Iron fluorides were particularly studied and the … Sr 2+ (or Ba 2+ ), Fe 3+ in HF-H 3 PO 4 -H 2 O solutions were especially studied in …

… Thus, one of the methods for the synthesis of magnetic alloys … of anhydrous mixtures of their trifluorides with iron(III) fluoride … of iron trifluoride with metallic platinum, nickel, and iron was …

… or ternary fluorides of lower valence. Sometimes dehydration of hydrated fluorides under … This technique is especially appropriate for ferric fluoride crystallization, because it can be used …

… fluoride is highly hygroscopic and difficult to be prepared in a single phase. Strong ionic bonding between Fe 3… Therefore, the preparation of FeF 3 with high purity and the improvement …

… scale-up of chemical processes is not such a trivial process … that helps to scale up chemical production processes for LCA … important calculations for the reaction step's energy use as …

… with the exception of hydrogen fluoride. In the pilot plant and … quantitatively with UV Inorganic impurities (including metals… Inorganic impurities can be quantified by residue on ignition …

… The process is straightforward to scale up and has also been … of experience in making high purity inorganic fluorides, such as NF3, … The chemical vapor purification process has been …

Abstract The development of low‐loss fluoride glass fibres for transoceanic telecommunications led to an increased demand for inorganic fluorides with ultrahigh purity in respect of transition metals, rare earths and oxygen. This review paper describes the Merck Ltd strategy for achieving a wide range of metallic fluorides using methods of preparation and purification selected for a combination of technical efficacy and economic practicability. General preparative methods involving aqueous and non‐aqueous routes are described, together with purification methods such as ion exchange, zone refining and vacuum sublimation. The special role of ammonium fluoride complexes is discussed. The application of these general methods to the manufacture of fluoride glass components is described, with special reference to the ZBLAN formulation. Additional glass compositions and their individual requirements are also discussed. The parallel application of high‐purity metal fluorides in the growth of optical crystals is emphasised, the history of fluoride ultrapurification having begun with the early demand for high‐quality UV and IR crystals such as CaF 2 and LiF.

AbstractAluminum fluoride (AlF3) is an essential industrial material widely used in … on the powder properties of its precursor, aluminum fluoride trihydrate (AFT). However, conventional …

Because direct roasting of aluminum fluoride hydrate will hydrolysis, resulting in higher alumina content in aluminum fluoride products. To solve this problem, a two-step process for the preparation of anhydrous AlF3 from AlF3·3H2O and NH4HF is described in this paper. First, AlF3·3H2O was dried at 220 ℃ for 9–12 h, and then NH4HF (the mass ratio of AlF3·3H2O to NH4HF was 1:20) was added, and the mixture was roasted from room temperature to 650 ℃. The results showed that the hydrolysis of aluminum fluoride can be avoided effectively by the two-step roasting method with NH4HF, the purity of the anhydrous AlF3 was 99.8 wt%, and the concentration of alumina, the main impurity, was less than 0.1 wt%.

… Typically, the preparation of anhydrous FeF 3 employs high … Herein, we synthesized a type of porous anhydrous FeF 3 with … rational structure design and the facile synthesis process can …