泛血管疾病 或心脑血管疾病 文献计量分析

Adaptive immunity is an important disease mediator of pulmonary vascular remodeling during pulmonary hypertension (PH) development, especially T‐cells lymphocytes. However, data for bibliometric analysis of T cell immunity in PH is currently vacant. This aimed to provide a comprehensive and visualized view of T‐cells research in PH pathogenesis and to lay a solid foundation for further studies.

Background: Acquired immunodeficiency syndrome is a malignant infectious disease caused by the human immunodeficiency virus (HIV). HIV gradually destroys the body’s immune system and weakens the body’s ability to resist diseases. People living with HIV may have a higher incidence of coronary heart disease than people without HIV. Method: A literature retrieval from January 1, 1993 to October 1, 2023 based on the Web of Science Core Collection database. CiteSpace6.2.R4, VOSviewer v1.6.19, and Microsoft Excel 2019 were utilized for analyzing the following terms: countries, institutions, authors, journals, references, and keywords. Results: There were 1144 articles. The highest number of articles is in the USA, followed by Italy. University of California System, Harvard University, and Johns Hopkins University were the top 3 most productive institutions with publications in this field of research. Journal of Infectious Diseases ranked first with the highest publications (532 records), followed by Immunology (362 records), and Cardiac Cardiovascular Systems (242 records). Keyword co-occurrence analysis showed antiretroviral therapy, myocardial infarction, and protease inhibitors, etc. Keyword cluster analysis obtained 13 categories, which were roughly divided into 3 themes: (1) cardiovascular disease that has occurred or may occur; (2) HIV acquisitions that have occurred; (3) risk factors for cardiovascular disease. Conclusion: The article obtained the hotspots and trends and provided references for subsequent research. Based on the keyword citation burst detection analysis, we speculated that heart failure, risk, subclinical atherosclerosis, infection, and association were the research hotspots in recent years, which had a certain predictive effect on the future research direction.

Abstract Background: Kawasaki disease is a systemic vascular disease with an unclear pathophysiology that primarily affects children under the age of five. Research on immune control in Kawasaki disease has been gaining attention. This study aims to apply a bibliometric analysis to examine the present and future directions of immune control in Kawasaki disease. Methods: By utilizing the themes “Kawasaki disease,” “Kawasaki syndrome,” and “immune control,” the Web of Science Core Collection database was searched for publications on immune control in Kawasaki disease. This bibliometric analysis was carried out using VOSviewers, CiteSpace, and the R package “bibliometrix.” Results: In total, 294 studies on immune control in Kawasaki disease were published in Web of Science Core Collection. The three most significant institutions were Chang Gung University, the University of California San Diego, and Kaohsiung Chang Gung Memorial Hospital. China, the United States, and Japan were the three most important countries. In this research field, Clinical and Experimental Immunology was the top-referred journal, while the New England Journal of Medicine was the most co-cited journal. The Web of Science Core Collection document by McCrindle BW et al. published in 2017 was the most cited reference. Additionally, the author keywords concentrated on “COVID-19,” “SARS-CoV-2,” and “multisystem inflammatory syndrome in children” in recent years. Conclusion: The research trends and advancements in immune control in Kawasaki disease are thoroughly summarised in this bibliometric analysis, which is the first to do so. The data indicate recent research frontiers and hot directions, making it easier for researchers to study the immune control of Kawasaki disease.

Abstract Introduction: This study endeavors to evaluate the distribution patterns and research frontiers within the international literature on the association between chronic kidney disease and cardiovascular diseases in the medical field, through bibliometric analysis and visualized information. Methods: The Web of Science Core Collection database was selected as the data source from 2010 to 2023, and articles related to the association between chronic kidney disease and cardiovascular diseases were retrieved. The article data were analyzed through CiteSpace for bibliometric mapping, involving the examination of keywords, references, country/region distributions, and institutional contributions to identify and understand the evolving research dynamics and frontiers in this interdisciplinary field. Results: A total of 2,936 publications on the association between chronic kidney disease and cardiovascular diseases were included. The country with the most publications was USA (n = 904), and the institution with the most publications was University of Pennsylvania (n = 116). The most frequent keywords were chronic kidney disease (n = 2,194), cardiovascular disease (n = 1,188), and mortality (n = 604). The top 20 keywords and top 10 references that burst during 2010 to 2023 were listed. Conclusion: The association between chronic kidney disease and cardiovascular diseases has sparked extensive research, particularly in high-prevalence areas. From 2010 to 2023, publications on the association between chronic kidney disease and cardiovascular diseases show a linear increase. Current research hotspots and frontiers are mainly in cardiovascular-kidney-metabolic syndrome; innovative therapies and drug impact; gut microbiome; Mendelian randomization analysis. Overall, our study offers a comprehensive scientometric analysis of the association between chronic kidney disease and cardiovascular diseases, providing valuable insights for both researchers and healthcare professionals in the field.

OBJECTIVE The treatment of chronic limb threatening ischemia (CLTI) involves a broad spectrum of therapies including many new and emerging techniques. To standardize results of studies examining this pathology and to allow critical analysis and comparison between studies, the Society for Vascular Surgery recommended reporting standard guidelines for the endovascular management of CLTI in 2016. Research studies that do not adhere to complete reporting standards are often more ambiguous in impact and external validity, leading to bias and misinformation that has potentially damaging effects on clinical decision making. We thus sought to examine adherence to, and factors associated with non-compliance with these recommended guidelines. METHODS A literature database search was conducted to include all clinical trials, randomized controlled trials, and retrospective comparative studies written in English examining the endovascular treatment of PAD/CLTI from January 2020 to August 2022. Systematic reviews, case reports and meta-analysis were excluded. The manuscripts were reviewed for adherence with the SVS guidelines (overall and by guideline subcategories based on demographics, treatment methods and outcomes), and factors associated with this adherence were determined. This data was used to calculate descriptive and comparative statistics. RESULTS 54 manuscripts were identified from this timeframe. On average, articles reviewed reported on 42.0% of the SVS reporting standards (range 25.0-65.2%, Fig 1) with 74.1% of articles (n=40) not adhering to at least 50.0% of the standards. Manuscripts most completely followed guidelines regarding "Patient Factors" and were least likely to demonstrate adherence to description of CLTI and study complications. Within the guideline subcategories, complete adherence to guidelines was not demonstrated in any manuscript in stent trials, disease outcome measures, technical outcome measures, patient factors and critical limb ischemia description, and complete adherence rates within the other subcategories was low (range 5.6-18.6%). Studies conducted within the United States and those with industry sponsorship were more likely to adhere to >50% of the reporting standards (p<0.05). Journal impact factor, year of publication, and number of authors had no correlation to the percent adherence to guidelines in specific categories or adherence overall. CONCLUSIONS Adherence to reporting standard guidelines for endovascular treatment of lower extremity PAD specifically outlined by the SVS is suboptimal regardless of the quality of the journal the research is published in. Increasing adherence to reporting standards to provide a framework for comparison of studies across techniques used should be prioritized by authors, journal editors, and vascular societies.

Background In recent years, the incidence of Kawasaki disease among the pediatric population has experienced a significant increase. With complications mainly affecting the cardiovascular system, Kawasaki disease has received widespread attention from scholars worldwide. Numerous articles on Kawasaki disease in children have been published far. However, there is a lack of studies that use visualization methods to perform a bibliometric analysis of the relevant literature. This study aims to obtain overall information on the output characteristics of publications on childhood Kawasaki disease between 2012 and 2022 through bibliometric analysis, identify research hotspots and frontiers, and provide new ideas and references for future clinical and scientific research. Methods Literature meeting the inclusion criteria was screened from the Web of Science Core Collection, PubMed, and Scopus databases. Visual analysis of the literature by country, institution, journal, author, keywords, and references was performed using Citespace (6.1.R6), VOSviewer (1.6.18), and the online bibliometric website (https://bibliometric.com/). Results A total of 4,867 eligible publications were included. The number of annual publications is generally rising, rapidly increasing since 2019. Among countries and institutions, China and KAOHSIUNG CHANG GUNG MEMORIAL HOSPITAL have the highest output of articles. With 104 publications, Ho-Chang Kuo has a high impact in the field of KD. The most cited author is Jane W. Newburger. The most prolific journal is FRONTIERS IN PEDIATRICS. CIRCULATION is the most frequently co-cited journal. The most popular keyword in frequency and centrality is “immunoglobulin”. The reference with the highest burst intensity was Verdoni L, LANCET, 2020. Conclusion Kawasaki disease in children remains a hot topic among pediatricians worldwide and is receiving increasing attention. We innovated the “national-institutional-journal” model, which promotes further international cooperation in this field. The hot topics in the field of pediatric KD are “KD pathogenesis”, “immunoglobulin resistance and complementary therapy”, and “cardiovascular complications”. Frontiers include disease-related (“multisystem inflammatory syndrome”, “coronavirus disease 2019”, “hypotension”), treatment-related (“procalcitonin”, “ anakinra”), and pathogenesis (“polymerase chain reaction”).

Vascular access is essential for effective hemodialysis, a life-sustaining treatment for patients with chronic kidney disease, and nurses play a critical role in its management through infection prevention, patient education, and promotion of self-care. Despite a growing body of research on vascular access, bibliometric analyses that specifically explore nursing contributions remain limited. This study aimed to analyze trends in nursing research on vascular access in hemodialysis through a bibliometric approach. A total of 837 articles published in 275 sources between 1986 and 2025 were retrieved from the Web of Science database using MeSH terms. The data were analyzed with Biblioshiny and VOSviewer to examine publication trends, citation patterns, co-citation, and collaboration networks. Findings indicated a steady growth in the field, with an annual publication increase of 1.79%. The most productive journals were Nephrology Nursing Journal (n = 57), Journal of Vascular Access (n = 46), and BMC Nephrology (n = 33). Leading authors included Sousa C.N. (n = 20), Teles P. (n = 15), and Johnson D.W. (n = 13). Co-citation and co-occurrence analyses revealed both technical topics such as arteriovenous fistulas and patient-centered themes including quality of life and self-care. International collaboration was evident, with 16% of studies involving multi-country authorship, reflecting the global relevance of this research area. The study highlights the influential role of a small group of authors and journals in shaping nursing research on vascular access in hemodialysis and indicates a growing emphasis on patient-centered approaches. These findings provide direction for future nursing research to support evidence-based practice and enhance patient outcomes.

Background: Peripheral Artery Disease is a condition affecting vessels that produces significant effects on quality of life and presents considerable challenges in clinical work. Exercise that provides treatment demonstrates an approach that does not use drugs and shows benefits, including improved capacity for exercise, reduced symptoms during walking, and enhanced circulation in vessels. However, research trends following over time, main areas of study, and developing characteristics in this area require systematic analysis combining studies. Objectives: This study examines research on exercise for Peripheral Artery Disease from 2015 to 2025 using an analysis of publications. The work aims to examine global patterns in research, to find main topics, and to describe networks of collaboration between researchers that relate to current understanding and clinical use of exercise for this condition. Methods: The study uses an approach that analyzes publications to examine 618 articles published between 2015 and 2025. Data come from various sources, and analysis focuses on measures such as publication volume, keywords, patterns of citation between studies, and networks of collaboration. Software for analysis provides visualization and finds groups of research, important authors, main journals, and contributions from institutions across the world. Results: Analysis shows a consistent increase in publications over the previous decade, with a high point in 2022. The United States appears as the main country in research on exercise for Peripheral Artery Disease, with substantial work from institutions such as Northwestern University and Harvard Medical School. Countries in Europe, particularly Germany, the United Kingdom, and the Netherlands, form additional groups of research, showing strong collaboration between countries in the study. Main journals such as the Journal of Vascular Surgery and Vascular Medicine provide the primary sources in the area, with a focus on outcomes in clinical settings, mechanisms of treatment, and strategies for rehabilitation. Conclusions: The area of exercise for Peripheral Artery Disease shows considerable development in the previous decade, with increasing research across different areas and collaboration across the world. This development occurs, but challenges continue in developing treatment approaches for individual patients and in establishing standard methods for measuring effects. Research in the future should focus on improving exercise approaches using the severity of Peripheral Artery Disease, examining mechanisms at the level of molecules, and enhancing integration of treatment using technology for distance care and technology for rehabilitation. This analysis of publications provides an important understanding of the study area for exercise in Peripheral Artery Disease and provides direction for additional development in clinical work and research.

Background In recent years, vascular aging has emerged as a hot topic in become an important direction of aging research, but a comprehensive bibliometric analysis has not been conducted. Methods The Web of Science database was searched for articles and reviews on vascular aging from January 1, 2014, to August 20, 2024, and the literature was analyzed and knowledge maps were constructed using CiteSpace, VOSviewer, pajek and Scimago Graphica software for econometric analysis and knowledge graph construction of the literature. Results A total of 38,910 authors from 7622 institutions in 111 countries published 7277 papers in 1344 academic journals, with a significant increase in publication volume. The United States is the country with the highest productivity and citation rates, and Mayo Clinic is the most active institution. Tarantini S published the most papers, while Csiszar A received the most citations. Retina-The Journal of Retinal and Vitreous Diseases journal published the most papers, and Circulation journal received the most citations. The main research aspects include age-related macular degeneration, arteriosclerosis, and oxidative stress, which are the main keywords in this field. In the last decade, the term c reactive protein has attracted great attention with its strongest citation explosion. Conclusion In the past decade, the research focus on vascular aging has been increasing year by year. Age-related macular degeneration, arteriosclerosis, oxidative stress and vascular endothelial cells are the emerging research directions in this field.

Panvascular diseases are a group of vascular system diseases, mainly including the heart, brain, neck, and other parts of the vascular lesions. As a non-pharmacological intervention, exercise therapy could prevent and treat Panvascular diseases. However, few bibliometric analyses of exercise therapy in Panvascular disease exist. This study aimed to analyze the trends and hotspots over the past decade and provide insights into the latest state of the art in global research, thereby contributing to further research in the field. We systematically searched the Web of Science Core Collection (WOSCC) for articles on exercise therapy and Panvascular disease. The acquired information from the reports was analyzed using CiteSpace and VOSviewer software to assess and forecast this field hottest areas and trends. The final analysis included 294 articles by our specified inclusion criteria. The number of publications has gradually increased over the past decade. Stroke was one of the most studied Panvascular diseases. China and the University of Sao Paulo were the country es and institutions that contributed the most to the field. Mary M. McDermott was the most prolific researcher, and the Journal of Vascular Surgery published the most articles. The 6-minute walk test, skeletal muscle, oxidative stress, and supervised exercise therapy were hot topics from 2019 to 2023. In conclusion, exploring exercise therapy programs and exercise mechanisms for Panvascular diseases has been ongoing. This study revealed the current status and trends of research in the field and identified hot topics. It was helpful for scholars to understand exercise therapy critical role in treating and preventing Panvascular diseases and provided a reference for clinical decision-making and further research.

No abstract available