药物合成用无水氟化铁的制备及其10吨/年规模化生产流程设计

Because direct roasting of aluminum fluoride hydrate will hydrolysis, resulting in higher alumina content in aluminum fluoride products. To solve this problem, a two-step process for the preparation of anhydrous AlF3 from AlF3·3H2O and NH4HF is described in this paper. First, AlF3·3H2O was dried at 220 ℃ for 9–12 h, and then NH4HF (the mass ratio of AlF3·3H2O to NH4HF was 1:20) was added, and the mixture was roasted from room temperature to 650 ℃. The results showed that the hydrolysis of aluminum fluoride can be avoided effectively by the two-step roasting method with NH4HF, the purity of the anhydrous AlF3 was 99.8 wt%, and the concentration of alumina, the main impurity, was less than 0.1 wt%.

… Preparation of amorphous fluorides Rhombohedral ferric fluoride, prepared by action of a gaseous HF flow at 600C on anhydrous ferric chloride, is placed in a platinum crucible in high…

… The hydrothermal treatment of ferric fluoride first evidenced the possibility to grow anhydrous transition metal fluorides in HF solutions at high temperature and high pressure (I). A lot of …

… In this work, an attempt is made to find the optimum conditions to synthesize anhydrous iron fluoride by direct F 2 -gas fluorination through the use of iron chlorides with different …

Fluorination of α-Fe2O3 by NH4HF2 has been analyzed in this study using simultaneous thermogravimetry and differential thermal analysis (TG-DTA), scanning electron microscopy (SEM), and X-ray powder diffraction (XRD). The results indicated that the mass ratio NH4HF2 to Fe2O3 has no influence on the fluorination process. The fluorination starts at room temperature, dominates at 175.6°C, and completes at 200°C with the formation of (NH4)3FeF6. With further heat-treatment, (NH4)3FeF6 progressively releases NH4F by the formation of NH4FeF4 at 258.1°C, then (NH4)0.18FeF3 at 320°C and finally FeF3 with minor FeF2 at 400°C. NH4F released during the decomposition of (NH4)3FeF6 will fluorinate the un-reacted Fe2O3.

… substitutions is that of rubidium iron tetrafluoride. This compound, … Bromine trifluoride is also an excellent reagent and solvent … of anhydrous HF. Crystals remained after evaporation of …

… It was subsequently found possible to prepare anhydrous fluorometallates … Anhydrous iron(III) chloride, in a nickel boat, was heated gradually to 300 in a stream of chlorine trifluoride. …

… trifluoride may be advantageously made by a dry process if hydrogen fluoride is manufactured on-site . In this process… patented process of reacting metallic tin with anhydrous hydrogen …

… In a first step a cooling to 80 8C the TPD program was started (108/min up weighted amount of the anhydrous iron(III) compound was to 500 8C, keeping for 30 min). Desorbed NH3 was …